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Instrumentation

J-815 Circular Dichroism Spectrophotometer

Provides structural analysis of chiral biomolecules, commonly used to investigate secondary structure of proteins. Also equipped with emission monochromator for fluorescence measurements.

Biacore T200 Surface Plasmon Resonance System

Sensitively measures interactions between various biomolecules to determine quantities such as binding affinity, kinetics, specificity, and concentration

MicroCal PEAQ-ITC Isothermal Titration Calorimeter

Characterizes interactions of biomolecules in solution by direct measurement of heat released or absorbed

ProteomeLab XL-I Analytical Ultracentrifuge

Measures macromolecular size and shape and studies macromolecular interactions by monitoring movement under a centrifugal field

Optima MAX-XP Tabletop Ultracentrifuge

Separates components in small volume samples at max speed of 100k RPM

Optima XPN-90 Floor Ultracentrifuge

Separates components in medium volume samples at max speed of 70k RPM

Avanti JXN-26 High-Speed Centrifuge

Separates components in medium - large volume samples at max speed of 25k RPM

AKTA Pure 25 M1 Protein Purification System

Automated liquid chromatography system for separation of biomolecules with a triple wavelength UV detector

C400 Bioanalytical Imaging System

Imaging system for gels and blots with UV, visible, chemiluminescent, and fluorescent capabilities

QuantStudio Real-Time Polymerase Chain Reaction System

Sensitively detects and quantifies nucleic acids

Typhoon IP Phosphorimager

Laser scanner that detects and quantifies radioisotopic signals stored on imaging plates

Dragonfly Crystal Robot

Liquid dispensing robot to automate preparation of plates containing solution gradients, commonly used to optimize conditions for macromolecular crystallization

Mosquito Crystal Robot

Liquid dispensing robot to automate set-up of macromolecular crystallization experiments