The Biophysics Instrumentation Core (BIC) Facility offers sophisticated instrumentation dedicated to characterizing biomolecular conformations and interactions, as well as equipment for the isolation and purification of macromolecules for subsequent detailed biophysical analysis. The BIC Facility is committed to fostering biophysical research at Notre Dame and elsewhere.

AUC home New instrument!

Multi-wavelength AUC

The BIC facility is excited to offer a new Optima A/I analytical ultracentrifuge thanks to an NIH S10 grant. AUC provides information on biomolecule size and shape and sample homogeneity; AUC can also be used to determine the molecular weight, association constants, and stoichiometry of macromolecular complexes. The new AUC is ready for use by researchers.
J-1500_300 New instrument!

J-1500 CD Spectropolarimeter

The BIC facility has purchased a Jasco J-1500 circular dichroism spectropolarimeter thanks to an NIH S10 basic instrumentation grant. CD provides structural analysis of chiral biomolecules, commonly used to examine secondary structure of proteins. The new CD is ready for use by researchers.
Typhoon RGB New instrument!

Typhoon RGB Scanner

The BIC facility is excited to offer a new Typhoon RGB laser scanner. The new scanner adds fluorescent imaging to its existing phosphor imaging capabilities. It is used to sensitively detect and quantify radiolabeled and fluorescently labeled nucleic acids and proteins.