The Biophysics Instrumentation Core (BIC) Facility offers sophisticated instrumentation dedicated to characterizing biomolecular conformations and interactions, as well as equipment for the isolation and purification of macromolecules for subsequent detailed biophysical analysis. The BIC Facility is committed to fostering biophysical research at Notre Dame and elsewhere.
New Real-Time qPCR System
The BIC Facility has acquired a QuantStudio 3 Real-Time Polymerase Chain Reaction System. Real-time qPCR sensitively detects and quantifies nucleic acids. The instrument will be available for use by researchers mid January.
New T200 SPR System
The BIC facility has purchased a Biacore T200 Surface Plasmon Resonance System thanks to an NIH S10 shared instrumentation grant. SPR sensitively measures interactions between biomolecules to determine quantities such as binding affinity, kinetics, specificity, and concentration. The new SPR is ready for use by Notre Dame researchers.
The BIC Facility recently upgraded its ProteomeLab analytical ultracentrifuge to add interference detection to its existing absorbance detection capabilities. The upgraded AUC is now available for use.