The Biophysics Instrumentation Core (BIC) Facility offers sophisticated instrumentation dedicated to characterizing biomolecular conformations and interactions, as well as equipment for the isolation and purification of macromolecules for subsequent detailed biophysical analysis. The BIC Facility is committed to fostering biophysical research at Notre Dame and elsewhere.
CTSI Pilot Funding Program
Indiana CTSI is now accepting applications for its Pilot Funding program, which provides funds to use CTSI designated core facilities (such as the BIC). The submission deadline is September 26, 2022. Click the image for more information.
New instrument!
New T200 SPR System
The BIC facility has purchased a Biacore T200 Surface Plasmon Resonance System thanks to an NIH S10 shared instrumentation grant. SPR sensitively measures interactions between biomolecules to determine quantities such as binding affinity, kinetics, specificity, and concentration. The new SPR is ready for use by Notre Dame researchers.
Upgrade!
Analytical ultracentrifuge
The BIC Facility recently upgraded its ProteomeLab analytical ultracentrifuge to add interference detection to its existing absorbance detection capabilities. The upgraded AUC is now available for use.