The Biophysics Instrumentation Core (BIC) Facility offers sophisticated instrumentation dedicated to characterizing biomolecular conformations and interactions, as well as equipment for the isolation and purification of macromolecules for subsequent detailed biophysical analysis. The BIC Facility is committed to fostering biophysical research at Notre Dame and elsewhere.
A ProteomeLab XL-A (Beckman Coulter) analytical ultracentrifuge will be available for use in early October 2019. Applications include characterizing macromolecular size and shape, and studying macromolecular interactions in solution.
A new Optima XPN-90 preparative ultracentrifuge will be available for use this fall. This centrifuge separates components in medium volume samples at max speed of 70k RPM. The current Optima Max-E tabletop ultracentrifuge will also be upgraded to a new Optima Max-XP tabletop ultracentrifuge.
The BIC Facility updated its isothermal titration calorimeter to a new MicroCal PEAQ-ITC, thanks to an internal Equipment Restoration and Renewal grant. The new instrument has been installed and is ready for use.